Affilin™ molecules are small non-immunoglobulin proteins which are designed for specific binding of proteins and small molecules. New Affilin™ molecules can be quickly selected from libraries which are based on two different human derived scaffold proteins
Affilin™ molecules which have, for example, been generated against steroid hormones, receptor domains and different cytokines, can be further modified for various applications. Additional functionalities can be generated through genetic fusions with enzymes or effector domains. Specific labeling, chemically or with isotopes, extends the field of applications for Scil Proteins individualised binding proteins.
Affilin™ proteins are easily produced in the cytoplasm of E. coli
and are fully functional without further posttranslational modifications such as glycosylation.
Affilin™ molecules will find their applications
in therapy, chromatography, in vivo
and in vitro
diagnostics and as research tools. Scil Proteins uses the proprietary Affilin™ technology to build up its own therapeutic and chromatographic product portfolio but is also open for partnerships with pharmaceutical and biotech companies in different application and indication fields.